Welcome to Crux Biolabs

A leading Australian bioanalytical lab for CROs, clinical, pre-clinical trials, contract research and more, dedicated to your success

Cell Culture, Functional Assays and PBMC Processing

PBMC processing and sample aliquoting. Crux Biolabs is accredited by NATA and our process has been validated in the Quality Assurance Program (QAP) by The Immunovirology Research Network’s (IVRN)

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ELISpot & Flurospot

ELISpot and FluoroSpot are highly sensitive functional assays for measuring antigen-specific T cells, which typically occur at low frequency in vivo. Crux Biolabs offers both ELISpot and FluoroSpot assays to support R&D and pre-clinical to clinical projects providing validation services using commercially available or custom assays.

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Flow Cytometry

Crux is accredited to ISO 17025 by NATA for flow cytometry. We can help design panels and run multi-color panels for your clinical or pre-clinical samples and have a CytoFlex flow cytometer, which has 13 colours (V5-B5-R3) and small particle capabilities.

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Design of customised biomarker panels and pre-validated inflammation panels to help detect multiple biomarkers, including cytokines, in very small volumes, with our Luminex® scientists validated by the Duke Human Vaccine Insitute EQAPOL program.

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About us

For more than a decade, Crux Biolabs have been an Australian leader – and we’re just getting started.

Crux Biolabs dedicates itself to being an extension of the research and testing team no matter how big or small. Efficient, agile, thorough, we pride ourselves on building long standing relationships with our clients and are heavily investing in growing our team and laboratory capacity to support the high demand from our global sponsors to test and deliver time and time again.


Service in focus:

We are expert immunologists

Our highly experienced scientists offer a full suite of immunology services, and have great expertise in bespoke test development and experience across a broad range of therapeutic areas for clients across the globe. We support PK end points and PD outputs for clinical trials, are experts at performing anti-drug antibody (ADA) assays and have experience working with a wide variety of large molecules.

Our team of scientists are experts at customising biomarker detection & cell assays.

Just some of our expert immunology services are listed here, or to find our more head to our detailed immunology page. Have a question or require a different set of tests? Get in touch - our teams of scientists are more than happy to help and show you what we can do.

  • Immunophenotyping including intracellular markers
  • Intracellular cytokine staining
  • CAR-T cell characteristion for cell therapy development
  • Receptor occupancy (RO) measurement
  • Internalisation assays
  • Antibody-dependent cellular phagocytosis assays
  • Phagocytosis assays
  • Phospho-flow cytometry
  • And more
Crux: Global Standards

Working Together

What sets us apart is our flexibility. We understand no two situations or requests are alike, which is why we seek to understand and create a custom solution to what you are after through our simple process


Our laboratory is NATA accredited to ISO 17025 and all our assay validation and reporting is compliant with major governing bodies

Best in class quality standards
Our PC2 laboratory in Melbourne is accredited by NATA to ISO 17025.

“The Crux team are dedicated scientifically to help and collaborate with the client. They play an integral role in our clinical trails immune-monitoring requirments. They are really nice people also.”

Dr Nick Ede

“Crux Biolabs have been critical to help Pio Therapeutics advance our lead program, and meet key pre-clinical value inflection points through the development of bioanalytical and primary cell-based functional assays. In all instances, Crux executed the work with a high degree of expertise, rigour and flexibility.”

Christopher Chan PhD

“With a treasure trove of patient samples collected from our clinical studies, we wanted a trusted CRO that could help us unlock the maximum scientific value from this precious resource. The team at Crux assisted in generating a meaningful work plan, that delivered high quality data and study reports, on time and within budget. We very much look forward to working with the lovely folks at Crux again.”

Dr John Wilkinson

“Working with Crux Biolabs was a seamless, easy and straightforward process. We were very pleased with the data output as well as expertise in assay set up and design.”

Alexandra Suchowerksa PhD

“Crux has a highly experienced and dynamic team that supported us throughout the whole lifecycle of our laboratory studies. They ensured that our complex biological samples were safely transported from overseas, went through Australian customs in a timely manner and were successfully used by their skilled scientists to produce high quality biomarker results.“

Eldin Rostom

Get in touch with our scientists

Have a question or want to know more? Our Australian-based team are ready. Get in touch via our contact form .